Karthik Bose recently presented his research at the American Physiology Summit in Long Beach, California. His work on cardiomyocyte endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) pathway is helping us better understand how heart cells respond to stress at the molecular level.
Our recent findings show how changes in the ER stress response reflect how heart tissue deals with challenges like oxidative stress during the critical period near birth. These changes can indicate whether the myocardium is already under stress or actively responding to regulatory signals. This insight is important because it helps explain why some heart cells undergo programmed cell death, which can affect heart development and function.
I also had the opportunity to present our latest research on circulating fetal troponin I as a biomarker for cardiomyocyte proliferation. Presenting alongside Karthik was a great chance to showcase different aspects of our work and connect with others in the field.
Sharing this work at the conference gave us a great chance to connect with other researchers and explore new ideas to move our research forward.